While some shooters may not like the idea of using a .22 for personal defense due to it being a smaller caliber, there are several reasons why this could be the perfect choice for someone. First off, a .22 is easy to shoot and easier to learn on. This makes it ideal for new shooters or younger family members. Ammunition is also cheap and easier to find, especially when compared to more typical handgun rounds such as 9 mm. Shooting a .22 is also much quieter than other rounds, making it more lucrative for backyard practice and indoor ranges.