The largest single-year drop in cancer mortality took place between 2016 and 2017, with the death rate falling by 2.2%. With lung cancer being the leading cancer resulting in death, a decreased death rate since the 1990s has spurred the overall cancer mortality rate to fall. The death rate for men has fallen by 51% and the rate for women has dropped by 26%. Lung cancer is still responsible for almost one fourth of cancer deaths, which is more than breast, prostate, and colorectal cancers combined. In 2020, 1,806,590 additional cancer cases and 606,520 cancer mortalities are estimated to occur in the United States.