Khan Saeed Sajna, the Mehsud splinter group leader of Tehreek-e-Taliban Pakistan (TTP), was killed in a US drone strike in North Waziristan, sources from Afghan government said.
In Tehreek-e-Taliban Pakistan, he was accused of being the closest to Pakistani military and the biggest supporter of Haqqani network.
The Express Tribune meanwhile reported that Khan Saeed Mehsud alias Sajna was killed in a drone strike in Margha area of Barmal in Afghanistan early Friday morning.
He was killed along with his nephew Ismail and two guards, The Express Tribune quoted sources.
This comes after Afghan and US forces have increased their airstrikes against militants.
In a recent move, the US Air Force B-52 bomber targeted Taliban hideouts in Badakhshan province, in bordering areas with China and Tajikistan.
Kandahar Police Chief General Abdul Raziq this week said all terrorist groups operating in Afghanistan have safe havens in Pakistan.